Vaccines News

June 10, 2025

Top Headlines

New mRNA Vaccine Is More Effective and Less Costly to Develop

June 3, 2025 — A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a new ...

Large-Scale Immunity Profiling Grants Insights Into Flu Virus Evolution

June 3, 2025 — A new study shows how person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a ...

Earlier Measles Vaccine Could Help Curb Global Outbreak

May 29, 2025 — The global measles outbreak must trigger an urgent debate into whether a vaccine should be recommended earlier to better protect against the highly contagious disease during infancy, a new review ...

HIV Vaccine Study Uncovers Powerful New Antibody Target

May 27, 2025 — In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains ...

Engineered Bacteria Can Deliver Antiviral Therapies, Vaccines

May 21, 2025 — New research demonstrates how specially engineered bacteria taken orally can operate as a delivery system for vaccines and antiviral ...

Two HIV Vaccine Trials Show Proof of Concept for Pathway to Broadly Neutralizing Antibodies

May 15, 2025 — A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional ...

Particles Carrying Multiple Vaccine Doses Could Reduce the Need for Follow-Up Shots

May 15, 2025 — New polymer microparticles can be used to deliver vaccines at different times. The work could lead to childhood vaccines given just once, eliminating the need for booster ...

New Study Offers Insights Into Designing Safe, Effective Nasal Vaccines

May 14, 2025 — Most vaccines -- and boosters -- are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease. But for respiratory diseases like COVID-19, it can be important to have ...

Yellow Fever Vaccination: How Strong Immune Responses Are Triggered

May 14, 2025 — Researchers show how specific immune cells are activated by the vaccine -- an important starting point for the development of new ...

Novel, Needle-Free, Live-Attenuated Influenza Vaccines With Broad Protection Against Human and Avian Virus Subtypes

May 9, 2025 — A research team has achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV). These innovative LAIV platforms offer potential to develop ...

Building Vaccines for Future Versions of a Virus

May 8, 2025 — AI model EVE-Vax provides clues about how a virus may evolve and the immune response it could ...

Evaluating the Safety and Efficacy of a Smallpox Vaccine for Preventing Mpox

May 8, 2025 — The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated ...

Latest Headlines

updated 11:44am EDT

Vaccines of the Future: Harnessing the Immune System for Long-Lasting Protection

May 7, 2025 — Scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune ...

Shingles Vaccine Lowers the Risk of Heart Disease for Up to Eight Years

May 5, 2025 — People who are given a vaccine for shingles have a 23% lower risk of cardiovascular events, including stroke, heart failure, and coronary heart disease, according to a recent study of more than a ...

Left or Right Arm? New Research Reveals Why Vaccination Site Matters for Immune Response

Apr. 28, 2025 — Scientists have uncovered why vaccines can elicit a stronger immune response if they are administered in the same ...

Clinical Trials to Test Vaccine Against Alzheimer's-Promoting Tau Protein

Apr. 23, 2025 — Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

B Cells Found to Be Crucial for Long-Term Vaccine Protection, New Study Shows

Apr. 23, 2025 — Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B ...

Experimental Bird Flu Vaccine Excels in Animal Models

Apr. 17, 2025 — A vaccine under development has demonstrated complete protection in mice against a deadly variant of the virus that causes bird flu. The work focuses on the H5N1 variant known as 2.3.4.4b, which has ...

Americans Don't Think Bird Flu Is a Threat, Study Suggests

Apr. 18, 2025 — A team led by researchers say public ignorance and apathy towards bird flu (highly pathogenic avian influenza, or HPAI) could pose a serious obstacle to containing the virus and preventing a ...

Experts Stress Importance of Vaccination Amidst Measles Outbreaks

Apr. 14, 2025 — Pediatric infectious diseases experts stress the importance of vaccination against measles, one of the most contagious viruses, which is once more spreading in the United ...

Nasal Spray H5N1 Avian Influenza Vaccine Developed

Apr. 8, 2025 — Scientists have pioneered an influenza virus vector-based nasal spray vaccine platform and developed a nasal spray H5N1 avian influenza vaccine. During the early COVID-19 pandemic, this platform ...

Viral 'Backbone' Underlies Variation in Rotavirus Vaccine Effectiveness

Apr. 8, 2025 — Researchers have shown that differences in the entire rotavirus genome -- not just its two surface proteins -- affect how well vaccines work, helping to explain why some strains are more likely to ...

New Research Boosts Future Whooping Cough Vaccines

Apr. 4, 2025 — New research could aid in improving whooping cough vaccines to once again push this disease toward eradication by targeting two key weaknesses in the ...

An Antiviral Chewing Gum to Reduce Influenza and Herpes Simplex Virus Transmission

Apr. 4, 2025 — Low vaccination rates for influenza viruses and the lack of an HSV vaccine underscore the need for a new approach to reduce viral transmission. Researchers have now used a clinical-grade antiviral ...

New Vaccine Concept Tackles Harmful Bacteria in the Intestine

Apr. 3, 2025 — In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning ...

Study Strengthens Link Between Shingles Vaccine and Lower Dementia Risk

Apr. 2, 2025 — A new analysis of a vaccination program in Wales found that the shingles vaccine appeared to lower new dementia diagnoses by 20% -- more than any other known ...

mRNA-Based COVID-19 Vaccines Train the 'Long-Term Memory' of the Immune System

Mar. 26, 2025 — Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

'Low-Sugar' Vaccine Can Provide Broad Immunity Against Coronavirus Variants

Mar. 25, 2025 — Early animal studies show that a single vaccine could protect the recipient from different variants of the coronaviruses that cause COVID-19, the flu and the common cold. In addition to creating ...

Growing Body of Evidence Links HPV With Heart Disease

Mar. 25, 2025 — In addition to causing several types of cancer, human papillomavirus (HPV) appears to bring a significantly increased risk of heart disease and coronary artery disease, according to a new ...

New Data on Mpox Vaccine Effectiveness

Mar. 19, 2025 — A study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer ...

New Understanding of B Cell Mutation Strategies Could Have Implications for Vaccines

Mar. 19, 2025 — New study demonstrates how high-affinity B cells 'bank' their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine ...

Vaccine May Improve Breast Cancer Treatment Outcomes

Mar. 18, 2025 — Researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen ...

Older Adults Might Be More Resistant to Bird Flu Infections Than Children

Mar. 13, 2025 — Older adults who were exposed to seasonal flu viruses that circulated prior to 1968 are more likely to have some protection against H5N1, and children would benefit more from H5N1 ...

The Relationship Between Gut Microbiota, Immunoglobulin A, and Vaccine Efficacy

Mar. 13, 2025 — A study has established the importance of immunoglobulin A, an antibody that is part of the immune system, in generating a response to pneumonia vaccines. Researchers have found that the absence of ...

Meningococcal Vaccine Found to Be Safe and Effective for Infants in Sub-Saharan Africa, Study Suggests

Mar. 12, 2025 — Researchers helped conduct an important new global health study that found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective for use in ...

Breakthrough in Next-Generation Polio Vaccines

Mar. 11, 2025 — A more affordable, lower-risk polio vaccine is on the horizon, research has ...

New Discovery to Accelerate Strep A Vaccine Efforts

Mar. 6, 2025 — Researchers have discovered how antibodies help to protect against contagious bacterial infections caused by Strep A, including strep throat. And the findings are already contributing to efforts to ...

Research Identifies Key Antibodies for Development of Broadly Protective Norovirus Vaccine

Mar. 5, 2025 — Scientists have discovered a strategy to fight back against norovirus, a leading cause of gastroenteritis worldwide. Their new study identifies powerful antibodies capable of neutralizing a wide ...

TB Vaccine Candidate Provides 'Elite' Protection

Mar. 5, 2025 — A live-attenuated tuberculosis (TB) vaccine candidate in development elicits a much more balanced and effective immune response compared to the existing vaccine used across much of the world, ...

From Dormant to Danger: How VZV Reactivation Is Driving Central Nervous System Infections

Feb. 27, 2025 — Researchers observed a rise in adult central nervous system (CNS) infections, primarily aseptic meningitis caused by the varicella zoster virus (VZV), post-2019. The researchers highlighted the ...

Immunity Against Seasonal H1N1 Flu Reduces Bird Flu Severity in Ferrets, Study Suggests

Feb. 26, 2025 — Pre-existing immunity against seasonal H1N1 flu might help explain why most reported human cases of H5N1 bird flu in the U.S. have not resulted in lethal ...

Designing Self-Destructing Bacteria to Make Effective Tuberculosis Vaccines

Feb. 25, 2025 — Working toward more effective tuberculosis (TB) vaccines, researchers have developed two strains of mycobacteria with 'kill switches' that can be triggered to stop the bacteria after they ...