Crohn's Disease News

June 10, 2025

Top Headlines

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 — Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

Treating Chronic Inflammatory Diseases With JAK Inhibitors

Mar. 17, 2025 — Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. Since their approval, the indications for these medical ...

Focus on the Gut-Liver Axis: Semisynthetic Bile Acid Has Anti-Inflammatory Effects on the Gut

Mar. 13, 2025 — A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

Possible Biomarker Identified for Crohn's Disease With Arthritis Type

Mar. 5, 2025 — People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential biomarker, according to new ...

Inflammation May Explain Stomach Problems in Psoriasis Sufferers

Jan. 20, 2025 — People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research. These changes in the gut could explain why psoriasis sufferers often have ...

Wearable Devices Can Detect and Predict Inflammatory Bowel Disease Flare-Ups

Jan. 16, 2025 — Data collected by wearable technology can identify disease flare-ups up to seven weeks in ...

Potential Culprit Identified in Lingering Crohn's Disease Symptoms

Dec. 19, 2024 — A study may explain why some patients with Crohn's disease continue to experience symptoms, even in the absence of ...

New Research on Chronic Inflammation Explores Potential Treatments for Chronic Diseases and Cancer

Dec. 4, 2024 — A recently published study on a new approach to understanding chronic inflammation could lead to new advancements in the treatment of many debilitating medical conditions, including ...

First Molecule Identified That Promotes Gut Healing While Inhibiting Tumour Progression

Nov. 20, 2024 — Researchers found a molecule that can both help the intestines to heal after damage and suppress tumour growth in colorectal cancer. The discovery could lead to new treatments for inflammatory bowel ...

Mapping 1.6 Million Gut Cells to Find New Ways Treat Disease

Nov. 20, 2024 — By combining 25 datasets, researchers have created the largest cohesive cell atlas of the human gut and uncovered a new way that stomach cells may play a role in Inflammatory Bowel ...

How Nerve Stimulation Could Ease Inflammatory Bowel Disease

Nov. 20, 2024 — A new study shows stimulating the vagus nerve in mice with colitis reduced stress-driven symptoms of inflammatory bowel disease by regulating SUMOylation, an immune response that triggers gut ...

Latest Headlines

updated 11:27am EDT

Researchers Discover New Bacterium That Causes Gut Immunodeficiency

Sep. 26, 2024 — Researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases. The team identified the bacterium, ...

A Potential Pathway May Guide New Therapies for Inflammatory Bowel Disease and Other Inflammatory Diseases

Aug. 22, 2024 — There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a ...

Lab-Grown 'Mini-Guts' Could Help in Development of New and More Personalized Treatments for Crohn's Disease

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ...

Major Cause of Inflammatory Bowel Disease Discovered

June 5, 2024 — Researchers have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing ...

Apply Single-Cell Analysis to Reveal Mechanisms of a Common Complication of Crohn's Disease

Apr. 24, 2024 — Study identifies key pathways underlying perianal fistula, a disease complication that is more prevalent and severe in African American ...

Scientists Discover the Cellular Functions of a Family of Proteins Integral to Inflammatory Diseases

Apr. 22, 2024 — In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) ...

New Inflammatory Bowel Disease Testing Protocol Could Speed Up Diagnosis

Apr. 16, 2024 — Patients with suspected inflammatory bowel disease (IBD) could benefit from better testing protocols that would reduce the need and lengthy wait for potentially unnecessary colonoscopies, a new study ...

Microplastics Make Their Way from the Gut to Other Organs

Apr. 15, 2024 — Researchers have found that microplastics -- are having a significant impact on our digestive pathways, making their way from the gut and into the tissues of the kidney, liver and ...

Hope for Treating Autoimmune Diseases

Apr. 3, 2024 — A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The Systemic Inflammation ...

Gene Analysis Generates Spatial Map of Intestinal Cells and Traces Their Trajectories During Gut Inflammation

Apr. 2, 2024 — Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are ...

Implantable Sensor Could Lead to Timelier Crohn's Treatment

Mar. 18, 2024 — Scientists have developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease. The approach offers long-term, real-time monitoring ...

New Understanding of the Gut Immune System May Hold Promise for Crohn's Disease Patients

Mar. 15, 2024 — Scientists uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn's disease. The discovery may help define how to treat patients with severe ...

Treating Newly-Diagnosed Crohn's Patients With Advanced Therapy Leads to Dramatic Improvements in Outcomes

Feb. 22, 2024 — A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, ...

Healthy Diet Early in Life Seems to Protect Against Inflammatory Bowel Disease

Jan. 31, 2024 — Having a high dietary intake of fish and vegetables at 1 year of age, and a low intake of sugar beverages, seems to protect against inflammatory bowel disease. These are the findings of a study with ...

Mood Interventions May Reduce Inflammation in Crohn's and Colitis

Jan. 24, 2024 — New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood ...

Researchers Reveal Prevalence of Persistent Symptoms in Patients With Microscopic Colitis

Dec. 13, 2023 — A new study examines how multiple factors contribute to the miscommunication and understanding of the digestive disease, microscopic ...

Comprehensive Guideline on Using Biomarkers for Monitoring Crohn's Disease

Nov. 17, 2023 — New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive ...

Early Life Exposure to Broccoli Sprouts Protects Against Colitis in Inflammatory Bowel Disease

Nov. 9, 2023 — High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease ...

Body Changes Up to Eight Years Before Inflammatory Bowel Disease Diagnosis

Nov. 7, 2023 — Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative ...

Risk of Serious Infection Even in Low-Active IBD

Nov. 1, 2023 — Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal ...

A Promising Target to Fight Inflammatory Bowel Diseases

Oct. 26, 2023 — Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of cell signalling pathways, leading to a chronic inflammatory response. ...

Fungi Used in Food Production Could Lead to New Probiotics

Oct. 26, 2023 — According to a new study, 2 fungi used to produce food products have potential probiotic effects on gut ...

Inflammatory Bowel Disease Linked to Atopic Dermatitis

Sep. 19, 2023 — Adults with atopic dermatitis (AD) have a 34 percent increased risk of developing new-onset inflammatory bowel disease (IBD) compared with individuals who do not have the skin condition, and children ...

Developing a Less Invasive Test for Inflammatory Bowel Disease

Sep. 7, 2023 — Millions of Americans have inflammatory bowel disease (IBD), which occurs in one of two forms: Crohn's disease or ulcerative colitis. Though the two have similar symptoms, they require different ...

Neonatal Stem Cells from the Heart Could Treat Crohn's Disease

July 28, 2023 — Research found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse ...

Nanomedicine for Treating Inflammatory Bowel Disease

July 17, 2023 — Chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. A ...

Scientists Link Genes to Diet in Inflammatory Bowel Disease

July 5, 2023 — A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in ...

Pathogenic Bacteria Use a Sugar in the Intestinal Mucus Layer to Infect the Gut, Study Shows

July 3, 2023 — A new study shows the sugar sialic acid, which makes up part of the protective intestinal mucus layer, fuels disease-causing bacteria in the gut. The findings suggest a potential treatment target for ...

Helping 'Good' Gut Bacteria and Clearing out the 'Bad' -- All in One Treatment

June 21, 2023 — Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective ...

New Research Identifies Cells Linking Chronic Psychological Stress to Inflammatory Bowel Disease

June 8, 2023 — For the first time, cells involved with the communication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, ...